Ovulation induction and ovarian tumours: the debate continues.

نویسنده

  • A Murad
چکیده

OBJECTIVE To critically review the published literature regarding the proposed association of ovarian stimulation and increased risk of ovarian tumors. DESIGN A medline search (1966-1997) was done to identify case reports and epidemiological studies relevant to the issue in question. Review articles and critical reappraisals in the form of comments on studies done were also used. RESULTS Various case reports, studies and review articles were identified as most relevant. CONCLUSION Despite a few studies showing an apparent association between ovulation induction and ovarian cancer, support for their results has not been forthcoming. From the available data a causal relationship is not substantiated. To settle this issue large prospective studies are needed. Meanwhile, close clinical surveillance of patients being treated with ovulation induction is required.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Surgical Ovulation Induction in Women with Polycystic Ovary Syndrome: A Systematic Review

Background: Currently clomiphene citrate is the first-line treatment to induce ovulation in women with polycystic ovarian syndrome (PCOS). Surgical therapy with laparoscopic ovarian drilling (LOD) may avoid or reduce the need for gonadotropins. Objective: To determine the effectiveness and safety of LOD compared with ovulation induction in subfertile women with clomiphene-resistant PCOS. Search...

متن کامل

Another two cases of ovarian tumours in women who had undergone multiple ovulation induction cycles.

Many questions have been raised recently about the possible association between ovulation induction and ovarian cancer. In order to contribute to the limited literature on this important issue, two cases of ovarian cancer in women who had multiple ovulation induction are presented here. In the first case the patient had ovarian induction by clomiphene citrate while she already had an ovarian cy...

متن کامل

Maternal Exposure to Second-hand Smoke and Super Ovulati on Outcome for Assisted Reproduction

Background The effect of smoking cigarettes is followed by diverse effects on ovaries and developing follicles but the effect of passive smoking on ovarian function is unknown. On the other hand, the ovarian response to induction is a very important step in assisted reproduction. The aim of this study is to compare ovarian response in passive smokers and non-passive smokers in an assisted repro...

متن کامل

P-165: Comparison of Urinary and Recombinant Human Chorionic Gonadotropin during Ovulation Induction in Intrauterine Insemination Cycles

Background: Urinary human chorionic gonadotropin is the most widely used medicine for ovulation in ovarian stimulation cycles. Recently however, recombinant HCG has also become commercially available. This study presents compare the use of recombinant hCG with urinary hCG during controlled ovarian hyperstimulation and intra uterine insemination (COH-IUI ) cycles Materials and Methods: This is s...

متن کامل

O-20: Slow-Freezing-Induced Changes of Birefringent Structures in Human Oocytes Are Related to Responsiveness to Ovulation Induction

Background: The slow-freezing method is one of the most popular techniques to freeze human oocytes and it is also used in routine in vitro-fertilization (IVF) programs, particularly in those countries where embryo freezing is not allowed. Slow-freezing damages some of the structures of the egg, among which the meiotic spindle (MS) and the zona pellucida (ZP). Polarized Light Microscopy (PLM) pe...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • JPMA. The Journal of the Pakistan Medical Association

دوره 48 11  شماره 

صفحات  -

تاریخ انتشار 1998